Featured Product
This Week in Quality Digest Live
Health Care Features
Etienne Nichols
How to give yourself a little more space when things happen
Chris Bush
Penalties for noncompliance can be steep, so it’s essential to understand what’s required
Jennifer Chu
Findings point to faster way to find bacteria in food, water, and clinical samples
Smaller, less expensive, and portable MRI systems promise to expand healthcare delivery
Lindsey Walker
A CMMS provides better asset management, streamlined risk assessments, and improved emergency preparedness

More Features

Health Care News
Showcasing the latest in digital transformation for validation professionals in life sciences
An expansion of its medical-device cybersecurity solution as independent services to all health systems
Purchase combines goals and complementary capabilities
Better compliance, outbreak forecasting, and prediction of pathogens such as listeria or salmonella
Links ZEISS research and capabilities in automated, high-resolution 3D imaging and analysis
Creates one of the most comprehensive regulatory SaaS platforms for the industry
Resistant to high-pressure environments, and their 3/8-in. diameter size fits tight spaces
Easy, reliable leak testing with methylene blue
New medical product from Canon’s Video Sensing Division

More News

Quality Digest

Health Care

ZEISS Invests in Life-Science Startup InSphero for 3D Cell Culture Research

Links ZEISS research and capabilities in automated, high-resolution 3D imaging and analysis

Published: Wednesday, April 19, 2023 - 12:00

(ZEISS: Oberkochen, Germany) -- ZEISS Ventures is investing in life-science startup InSphero to further advance the adoption of 3D microtissues in research and drug development. InSphero AG, a pioneer in 3D spheroid and cell-based assays in pharmaceutical drug discovery and safety testing, has raised an eight-figure amount in its latest funding round. It will utilize the proceeds to commercialize its cryopreservation technology to enable further growth and scalability. ZEISS Ventures is participating in the financing round, along with internal and external investors.

InSphero’s comprehensive solutions for preclinical drug safety and efficacy testing are based on 3D microtissues, which are phenotypic models of the smallest functional unit of a tissue or organ. These drug-discovery and testing platforms combine scalable 3D technology, ISO quality-controlled 3D human tissue models, 3D-optimized media, as well as tailored assay services and support. Drug discovery partners immediately gain access to the depth and breadth of InSphero’s experience in developing and applying 3D models for liver toxicology, metabolic diseases, and oncology.

ZEISS Ventures invests in life-science startup InSphero to drive 3D cell culture research.

“The market for complex 3D in-vitro models is very attractive and is experiencing new tailwinds with the FDA Modernization Act,” says Gerrit Schulte, head of ZEISS Ventures. “This act elevates alternative methods for drug development to the same level as animal testing. InSphero has uniquely positioned itself with its highly industrialized platform solution to address this market opportunity.”

Dr. Jan Lichtenberg, CEO and co-founder of InSphero, says, “The widespread use of 3D microtissues following the ratification of the FDA Modernization Act requires efficient, automation-compatible, and scalable 3D models quickly. Our groundbreaking, cryopreserved ARCTis 3D microtissue portfolio offers a storable, always ready-to-use solution to efficient and insightful compound testing. We are on the way to becoming the biggest 3D microtissue biobank in the world.”

“The strategic investment in InSphero is perfectly aligned with our strategic initiative—life-science industrialization,” says Dr. Michael Albiez, head of ZEISS research microscopy solutions. “We will leverage the ZEISS know-how and establish our technologies as a key enabler for widely adopted and standardized workflows in applied life sciences and healthcare. We look forward to intensive collaboration with InSphero to provide customers with end-to-end workflows.”


About The Author

Quality Digest’s picture

Quality Digest

For 40 years Quality Digest has been the go-to source for all things quality. Our newsletter, Quality Digest, shares expert commentary and relevant industry resources to assist our readers in their quest for continuous improvement. Our website includes every column and article from the newsletter since May 2009 as well as back issues of Quality Digest magazine to August 1995. We are committed to promoting a view wherein quality is not a niche, but an integral part of every phase of manufacturing and services.