Featured Product
This Week in Quality Digest Live
Health Care Features
Michael King
Augmenting and empowering life-science professionals
Meg Sinclair
100% real, 100% anonymized, 100% scary
Kristi McDermott
Technology and what the future requires for patients and providers to thrive
Alonso Diaz
Consulting the FDA’s Case for Quality program
Scott A. Hindle
Part 7 of our series on statistical process control in the digital era

More Features

Health Care News
Recognized among early adopters as a leading innovation for the life sciences industry
Study of intelligent noise reduction in pediatric study
Streamlines annual regulatory review for life sciences
The company is also facilitating donations to the cause
Mass spectromic analysis from iotaSciences
Showcasing the latest in digital transformation for validation professionals in life sciences
An expansion of its medical-device cybersecurity solution as independent services to all health systems
Purchase combines goals and complementary capabilities
Better compliance, outbreak forecasting, and prediction of pathogens such as listeria or salmonella

More News

Sharona Hoffman

Health Care

Biased AI Can Be Bad for Your Health

Here’s how to promote algorithmic fairness

Published: Wednesday, April 7, 2021 - 11:02

Artificial intelligence holds great promise for improving human health by helping doctors make accurate diagnoses and treatment decisions. It can also lead to discrimination that can harm minorities, women, and economically disadvantaged people.

The question is, when healthcare algorithms discriminate, what recourse do people have?

A prominent example of this kind of discrimination is an algorithm used to refer chronically ill patients to programs that care for high-risk patients. A study in 2019 found that the algorithm favored whites over sicker African Americans in selecting patients for these beneficial services. This is because it used past medical expenditures as a proxy for medical needs.

Poverty and difficulty accessing healthcare often prevent African Americans from spending as much money on healthcare as others. The algorithm misinterpreted their low spending as indicating they were healthy, and deprived them of critically needed support.

As a professor of law and bioethics, I have analyzed this problem and identified ways to address it.

How algorithms discriminate

What explains algorithmic bias? Historical discrimination is sometimes embedded in training data, and algorithms learn to perpetuate existing discrimination.

For example, doctors often diagnose angina and heart attacks based on symptoms that men experience more commonly than women. Women are consequently underdiagnosed for heart disease. An algorithm designed to help doctors detect cardiac conditions that is trained on historical diagnostic data could learn to focus on men’s symptoms and not on women’s, which would exacerbate the problem of underdiagnosing women.

Also, AI discrimination can be rooted in erroneous assumptions, as in the case of the high-risk care program algorithm.

In another instance, electronic health-records software company Epic built an AI-based tool to help medical offices identify patients who are likely to miss appointments. It enabled clinicians to double-book potential no-show visits to avoid losing income.

Because a primary variable for assessing the probability of a no-show was previous missed appointments, the AI disproportionately identified economically disadvantaged people. These are people who often have problems with transportation, child care, and taking time off from work. When they did arrive at appointments, physicians had less time to spend with them because of the double-booking.

Some algorithms explicitly adjust for race. Their developers reviewed clinical data and concluded that generally, African Americans have different health risks and outcomes from others, so they built adjustments into the algorithms with the aim of making the algorithms more accurate.

But the data these adjustments are based on is often outdated, suspect, or biased. These algorithms can cause doctors to misdiagnose Black patients and divert resources away from them.

For example, the American Heart Association heart-failure risk score, which ranges from 0 to 100, adds three points for non-Blacks. It thus identifies non-Black patients as more likely to die of heart disease. Similarly, a kidney stone algorithm adds three of 13 points to non-Blacks, thereby assessing them as more likely to have kidney stones. But in both cases, the assumptions were wrong. Though these are simple algorithms that are not necessarily incorporated into AI systems, AI developers sometimes make similar assumptions when they develop their algorithms.

Algorithms that adjust for race may be based on inaccurate generalizations and could mislead physicians. Skin color alone does not explain different health risks or outcomes. Instead, differences are often attributable to genetics or socioeconomic factors, which are what algorithms should adjust for.

Furthermore, almost 7 percent of the population is of mixed ancestry. If algorithms suggest different treatments for African Americans and non-Blacks, how should doctors treat multiracial patients?

Promoting algorithmic fairness

There are several avenues for addressing algorithmic bias: litigation, regulation, legislation, and best practices.

1. Disparate impact litigation: Algorithmic bias does not constitute intentional discrimination. AI developers and doctors using AI likely do not mean to hurt patients. Instead, AI can lead them to unintentionally discriminate by having a disparate impact on minorities or women. In the fields of employment and housing, people who feel that they have suffered discrimination can sue for disparate impact discrimination. But the courts have determined that private parties cannot sue for disparate impact in healthcare cases. In the AI era, this approach makes little sense. Plaintiffs should be allowed to sue for medical practices resulting in unintentional discrimination.

2. FDA regulation: The U.S. Food and Drug Administration (FDA) is working out how to regulate healthcare-related AI. It is currently regulating some forms of AI and not others. To the extent that the FDA oversees AI, it should ensure that problems of bias and discrimination are detected and addressed before AI systems receive approval.

3. Algorithmic Accountability Act: In 2019, Senators Cory Booker and Ron Wyden and Rep. Yvette D. Clarke introduced the Algorithmic Accountability Act. In part, it would have required companies to study the algorithms they use, identify bias, and correct problems they discover. The bill did not become law, but it paved the path for future legislation that could be more successful.

4. Make fairer AIs: Medical AI developers and users can prioritize algorithmic fairness. It should be a key element in designing, validating, and implementing medical AI systems, and healthcare providers should keep it in mind when choosing and using these systems.

AI is becoming more prevalent in healthcare. AI discrimination is a serious problem that can hurt many patients, and it’s the responsibility of those in the technology and healthcare fields to recognize and address it.The Conversation

This article is republished from The Conversation under a Creative Commons license. Read the original article.


About The Author

Sharona Hoffman’s picture

Sharona Hoffman

Sharona Hoffman is a professor of health law and bioethics at Case Western Reserve University.